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Catenin-(delta)1 (G224) pAb

Catenin-(delta)1 (G224) pAb

Cat no: BS2992

Supplier: Bioworld Technology, Inc.
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The (alpha), (beta), (delta), and (gamma) -catenins are proteins that bind to the highly conserved, intracellular cytoplasmic tail of E-cadherin. (delta)-catenin interacts with Presenilin 1 and is expressed in the brain. The gene encoding (delta)-catenin maps to human chromosome 5p15.2. A hemizygous loss of the gene encoding (delta)-catenin leads to the mental retardation associated with Cri-du-Chat syndrome. (gamma)-catenin, also known as plakoglobin, is an 80-88 kDa protein that binds (alpha)-catenin and N-cadherin. In addition, the transmembrane phosphatase PTPm associates with catenin/cadherin complexes and may regulate complex signaling.
Catalogue number: BS2992
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: O60716
Dilutions: WB: 1:500~1:1000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 201-250 of Human Catenin-(delta)1.
Species: Catenin-(delta)1 (G224) pAb detects endogenous levels of Catenin-(delta)1 protein.
Molecular weight: ~ 108 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Catenin (delta)1; Catenin delta-1; Cadherin-associated Src substrate; Short name=CAS; p120 catenin; p120(ctn); p120(cas); CTNND1; KIAA0384
Additional info: For research use only, not for use in diagnostic procedure.

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