Home  >  Products  >  CBX8 (chromobox homolog 8 (Pc class homolog, Drosophila), Chromobox protein homolog 8, hPc3, HPC3, Pc3, PC3, Polycomb 3 Homolog, RC1, Rectachrome 1)
CBX8 (chromobox homolog 8 (Pc class homolog, Drosophila), Chromobox protein homolog 8, hPc3, HPC3, Pc3, PC3, Polycomb 3 Homolog, RC1, Rectachrome 1)

CBX8 (chromobox homolog 8 (Pc class homolog, Drosophila), Chromobox protein homolog 8, hPc3, HPC3, Pc3, PC3, Polycomb 3 Homolog, RC1, Rectachrome 1)

Cat no: C2098-87B

Supplier: United States Biological
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The family of Heterochromatin Proteins ("Chromobox Homolog", CBX) are highly conserved adapter molecules, which have important functions in the cell nucleus. These functions include gene repression by heterochromatin formation, transcriptional activation, regulation of binding of cohesion complexes to centromere, sequesteration of genes to nuclear periphery, transcriptional arrest, maintenance of heterochromatin integrity, gene repression at single nucleosome level and gene repression by heterochromatization of euchromatin. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.5-2ug/ml Optimal dilutions to be determined by the researcher. Positive Control: NIH/3T3 nuclear extract, HeLa cell nuclear extract Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C2098-87B
Reactivities: Human, Mouse
Hosts: Rabbit
Applications: Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris-Glycine, pH 7.4, 150mM sodium chloride, 0.05% sodium azide.
P type: Pab
Purity: Purified by Protein A affinity chromatography with GST depletion.
Additional info: Recognizes the postchromo domain of CBX8. Species Crossreactivity: mouse, human.

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