Home  >  Products  >  CBX8 (Chromobox Protein Homolog 8, Polycomb 3 Homolog, Pc3, HPC3, Rectachrome 1, PC3, RC1)
CBX8 (Chromobox Protein Homolog 8, Polycomb 3 Homolog, Pc3, HPC3, Rectachrome 1, PC3, RC1)

CBX8 (Chromobox Protein Homolog 8, Polycomb 3 Homolog, Pc3, HPC3, Rectachrome 1, PC3, RC1)

Cat no: C2098-89C

Supplier: United States Biological
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Chromobox homolog 8 (CBX8 or Pc3) is a member of Drosophila Polycomb group gene family. The polycomb group (PcG) genes are essential for maintenance of appropriate expression patterns of developmental master regulators and thus are essential for proper development. Changes in expression of PcG proteins have been associated with cancer. CBX8 is involved in maintaining the transcriptionally repressive state of genes. It modifies chromatin, rendering it heritably changed in its expressibility. Structurally, CBX4 contains 1 chromo domain, which is 40-50aa long. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.1-0.3ug/ml Optimal dilutions to be determined by the researcher. Positive Control: K562 lysate Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2098-89C
Reactivities: Human
Hosts: Goat
Applications: Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Additional info: Recognizes human CBX8. Species sequence homology: bovine, mouse.

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