Home  >  Products  >  CD23 (Low Affinity Immunoglobulin epsilon Fc Receptor, Fc-epsilon-RII, Lymphocyte IgE Receptor, Fcer2, Fcer2a, Fce2, FC epsilon RII, Low-affinity IgE Receptor, Ly-42)

CD23 (Low Affinity Immunoglobulin epsilon Fc Receptor, Fc-epsilon-RII, Lymphocyte IgE Receptor, Fcer2, Fcer2a, Fce2, FC epsilon RII, Low-affinity IgE Receptor, Ly-42)

Cat no: C2274-05B


Supplier: United States Biological
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CD23 is a 45kD protein, also known as low affinity IgE Fc receptor, FceRII, BLAST-2, Ly-42, or B6. It is a member of the Ig family, expressed on conventional B (but not B-1) cells and follicular dendritic cells. CD23 responds to high levels of IgE by downregulating IgE secretion. This antibody is useful for blocking IgE activity in vivo. Applications: Suitable for use in Flow Cytometry, Immunohistochemistry, Immunofluorescence and Immunoprecipitation. Other applications not tested. Recommended Dilution: Flow Cytometry: (same/less than)0.25ug/10e6 cells in 100ul volume Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2274-05B
Reactivities: Mouse
Hosts: Rat
Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation
Size: 500ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
P type: Mab
Isotype: IgG2a,k
Purity: Purified by immunoaffinity chromatography.
References: 1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press. 2. Delespesse G, et al. 1992. Immunol. Rev. 125:77. 3. Flores-Romo L, et al. 1993. Science 261:1038.
Additional info: Recognizes mouse CD23.

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