CD239, known as basal cell adhesion molecule or Lutheran blood group glycoprotein, is a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five N-terminus extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vasoocclusion of red blood cells in sickle cell anemia. Two different isoforms have been found for CD239.
Applications:
Suitable for use in Western Blot, Immunohistochemistry, Immunoprecipitation and Flow Cytometry. Other applications not tested.
Recommended Dilution:
Western Blot: 1:10,000-1:50,000
Immunohistochemistry: 1:50-1:100
Immunoprecipitation: 1:10-1:100
Flow Cytometry: 1:10-1:100
Optimal dilutions to be determined by the researcher.
Storage and Stability:
May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Manufactured incorporating RabMAb(R) technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.