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CD59 Glycoprotein (Antigen P18-20 Identified By Monoclonal Antibodies 16.3A5, EJ16, EJ30, EL32 And G344) (CD59)

CD59 Glycoprotein (Antigen P18-20 Identified By Monoclonal Antibodies 16.3A5, EJ16, EJ30, EL32 And G344) (CD59)

Cat no: C2413-22C

Supplier: United States Biological
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Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. Applications: Suitable for use in Flow Cytometry, Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested. Recommended Dilution: Flow Cytometry: 1ug/ml Western Blot: 1-2ug/ml Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2413-22C
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot
Size: 50ug
Form: Supplied as a liquid in PBS, 15mM sodium azide, pH 7.4.
P type: Mab
Isotype: IgG2b
Purity: Purified by Protein A affinity chromatography.
Additional info: Recognizes human CD59. Species sequence homology: Mouse.

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