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CD68 (Macrosialin, Gp110)

CD68 (Macrosialin, Gp110)

Cat no: C2423-06F

Supplier: United States Biological
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CD68 is a 110 kD glycoprotein, known as macrosialin, belongs to sialomucin family and is closely related to the family of acidic, highly glycosylated lysosomal-associated membrane proteins (lamps). CD68 is predominately expressed in cytoplasmic granules of monocytes/macrophages, dendritic cells, and granulocytes. It is one of the useful myeloid cell markers. Further studies have shown that CD68 is also expressed by a subset of hematopoietic progenitors, gamma/delta T cells, NK cells, LAK cells, subset of B cells, fibroblasts, and endothelial cells. The biological function of CD68 is still unknown. Applications: Suitable for use in Flow Cytometry and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2423-06F
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Immunohistochemistry
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
P type: Mab
Isotype: IgG2b,k
Purity: Purified by immunoaffinity chromatography.
References: 1. Doussis, IA., et al. 1993. J. Clin. Pathol. 46:334. 2. Davey, FR., et al., 1988. J. Clin. Pathol. 41:753. 3. Holness, CL., and Simmons, D.L., 1993. Blood 81:1607. 4. Gottfried, E., et al. 2008. Scand. J. Immunol. 67:453. 5. Hameed, A., et al. 1994. Hum. Pathol. 25:872.
Additional info: Recognizes human CD68.

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