DBC-1 (Q455) pAb

Cat no: BS2331

Supplier: Bioworld Technology, Inc.

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Description
Additional Information

DBC1 (deleted in bladder cancer 1), also known as DBCCR1 or FAM5A, is a novel 761 amino acid cytoplasmic protein that functions as an essential regulator of tumorigenesis and mediates expression of components of the plasminogen pathway. Evolutionarily conserved and highly expressed in brain, DBC1 is found at weak levels in small intestine, lung, kidney, testis, prostate, thymus, heart and kidney. DBC1 contains one MACPF domain, belongs to the FAM5 family and inhibits cell proliferation at the G1S transition via negative regulation. DBC1 contains a 5' CpG island that, when hypermethylated, leads to silencing in 50 percent of bladder cancer cell lines.

Catalogue number:	BS2331
Reactivities:	Human
Hosts:	Rabbit
Applications:	Western Blot
Size:	100ug/100ul
Swiss prot:	Q8N163
Dilutions:	WB: 1:500~1:1000
Form:	liquid
Storage buffer:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration:	1ug/ul
Antigen:	Synthetic peptide, corresponding to amino acids 420-476 of Human DBC-1.
Species:	DBC-1 (Q455) pAb detects endogenous levels of DBC-1 protein.
Molecular weight:	~102 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp:	Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names:	KIAA1967
Additional info:	For research use only, not for use in diagnostic procedure.

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DBC-1 (Q455) pAb

Cat no: BS2331

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