DGK-delta (S66) Peptide

Diacylglycerol kinases (DGKs) phosphorylate diacylglycerol (DAG) to produce phosphatidic acid. DAG and phosphatidic acid are lipids that act as second messengers in signaling cascades. DGK-alpha influences cell activation and secretion of lethal exosomes, which in turn control cell death. DGK-beta is abundant in restricted brain regions such as the caudate putamen and olfactory tubercle. DGK-gamma encodes full-length and truncated transcripts that are present in a range of human tissues, with greatest expression observed in retina. DGK-delta is most abundant in skeletal muscle. DGK-E shows specificity for arachidonylcontaining diacylglycerol and is expressed predominantly in testis. DGK-0 is most abundant in the cerebellum and hippocampus. DGK-? is present in brain and retina as a predominant transcript of more than 12 kb, including a long 3-prime untranslated region, with additional low abundance transcripts of 9.5 and 7.5 kb. DGK-? is closely related to DGK-delta. DGK-? is most abundant in brain and muscle. DGKs have structural motifs that play regulatory roles, and these motifs form the basis for dividing the DGKs into five subtypes.

Prices direct from Bioworld Technology, Inc.

Quick response times

Exclusive Biosave savings/discounts

SPECIFICATIONS

Catalog Number

BS2078P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide DGK-delta (S66). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

Q16760

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS2078 DGK-delta (S66) pAb.

Alternative Names

Diacylglycerol kinase delta; DAG kinase delta; 130 kDa diacylglycerol kinase; Diglyceride kinase delta; DGK-delta; DGKD; KIAA0145; DGKdelta; DGK delta