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FGF-19:Fc, Recombinant, Human (Fibroblast Growth Factor 19)

Cat no: 044796


Supplier: United States Biological
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FGF-19 (Fibroblast growth factor 19) is involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. FGF-19 plays an important role in brain development during embryogenesis. FGF-19 binds only to FGF receptor 4 (FGFR4). Activity requires the presence of KLB. Sequence: Signal peptide and human FGF-19 (aa 1-216) are fused at the C-terminus the Fc portion of human IgG1. Storage and Stability: Short-term Storage: +4 degrees C Long-term Storage: -20 degrees C Stable for at least 6 months after receipt when stored at -20 degrees C. Working aliquots are stable for up to 3 months when stored at -20 degrees C.
Catalogue number: 044796
Size: 10ug
Form: Supplied as a lyophilized powder from a 0.2um-filtered solution in PBS, pH 7.2.
Purity: >90% (SDS-PAGE)
Alternative names: Fibroblast Growth Factor 19

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