GDI1 Peptide

Rab proteins, a family of Ras-related small GTP-binding proteins, play a key role in regulating intracellular vesicle trafficking. Rab GDP dissociation inhibitor (Rab GDI or GDI3) forms a soluble complex with Rab proteins and thereby prevents the exchange of GDP for GTP. In mammals, there exist two major isoforms, Rab GDI alpha (also known as XAP-4) and Rab GDI beta. While the mammalian Rab GDI beta-genes are ubiquitously expressed, the Rab GDI alpha genes are predominantly brain-specific. Since it is expressed predominantly in neural and sensory tissues, Rab GDI alpha may serve a specific function in neural signalmtransmission. The gene sequences for the Rab GDI proteins are extremely conserved in evolution, with substantial homology preserved across three eukaryotic kingdoms.

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SPECIFICATIONS

Catalog Number

BS5731P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide GDI1. (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

P31150

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS5731 GDI1 pAb.

Alternative Names

Rab GDP dissociation inhibitor alpha; Rab GDI alpha; Rab GDI alpha; Rab GDIalpha; RabGDIalpha; Guanosine diphosphate dissociation inhibitor 1; GDI-1; Oligophrenin-2; Protein XAP-4; GDIL; OPHN2; RABGDIA; XAP4