GFRalpha-1 (K90) Peptide

Cat no: BS1141P

Supplier: Bioworld Technology, Inc.

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Description
Additional Information

Glial cell line-derived neurotrophic factor (GDNF) and the related neurotrophic factor neurturin (NTN) are potent survival factors for central and peripheral neurons. GDNF is a glycosylated, disulfide-bonded homodimer that is distantly related to the TGFbeta superfamily of growth factors. Three receptors for these factors, GFRalpha-1 (also designated GDNFR-alpha, RETL1 or TrnR-1), GFRalpha-2 (also designated GDNFR-beta, RETL2, NTNR-alpha or TrnR-2) and GFRalpha-3 have been identified. The receptors do not contain transmembrane domains and are attached to the cell membrane by glycosyl-phosphoinositol linkage. Both GFRalpha-1 and GFRalpha-2 have been shown to mediate the GDNF-dependent and NTN-dependent phosphorylation and activation of the tyrosine kinase Ret. GFRalpha-3 is expressed only during development.

Catalogue number:	BS1141P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P56159
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide GFRalpha-1 (K90). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	GDNF family receptor alpha-1; GDNF receptor alpha-1; GDNFR-alpha-1; GFR-alpha-1; RET ligand 1; TGF-beta-related neurotrophic factor receptor 1; GFRA1; GDNFRA; RETL1; TRNR1; GFRalpha1; GFR alpha1; GFR alpha-1; GFR alpha1
Additional info:	This peptide can be used with studies using BS1141 GFRalpha-1 (K90) pAb.

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GFRalpha-1 (K90) Peptide

Cat no: BS1141P

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