GFRalpha-4 (P178) Peptide

Cat no: BS3304P

Supplier: Bioworld Technology, Inc.

0 reviews | Write a Review Pencil

Description
Additional Information

Glial cell line-derived neurotrophic factor (GDNF) and the related neurotrophic factor neurturin (NTN) are potent survival factors for central and peripheral neurons. Receptors for these factors include GFRalpha-1 (previously designated GDNFR-alpha), GFRalpha-2 (also designated RETL2), GFRalpha-3 and GFRalpha-4 (also known as persephin receptor). The receptors do not contain transmembrane domains and are attached to the cell membrane by glycosylphosphoinositol linkage. Binding of GDNF or NTN to one of these receptors leads to the activation of the tyrosine kinase Ret. GFRalpha-4 mediates the activation and GDNF-induced autophosphorylation of the RET receptor. It is mainly expressed in the adult thyroid gland, but lower levels may also be detected in fetal adrenal and thyroid glands.

Catalogue number:	BS3304P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	Q9GZZ7
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide GFRalpha-4 (P178). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	GDNF family receptor alpha-4; GDNF receptor alpha-4; GDNFR-alpha-4; GFR-alpha-4; Persephin receptor; GFRA4
Additional info:	This peptide can be used with studies using BS3304 GFRalpha-4 (P178) pAb.

See Full Product Listings >

GFRalpha-4 (P178) Peptide

Cat no: BS3304P

Get Quote

About Biosave

Product Categories

Information


Get a Quote Direct from Bioworld Technology, Inc.




By submitting this form you agree to your details being passed to Bioworld Technology, Inc. for the purpose of generating the best quote*