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GluR-delta2 (G860) Peptide

GluR-delta2 (G860) Peptide

Cat no: BS3029P

Supplier: Bioworld Technology, Inc.
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Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamategated, cation-specific ion channels. Kainate/AMPA receptors co-localize with NMDA receptors in many synapses and consist of seven structurally related subunits, designated GluR-1 to -7, as well as GluR-delta2. The kainate/AMPA receptors are primarily responsible for the fast excitatory neurotransmission by glutamate whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: E1, 2, 3, 4 and one ? subunit. The ? subunit is expressed throughout the brainstem whereas the four E subunits display limited distribution. In mice, mutations in the gene encoding GluR-delta2 (GRID2) cause the Lurcher phenotype. The gene encoding human GluR-delta2 maps to chromosome 4q22.
Catalogue number: BS3029P
Applications: Block/Neutralize/Inhibit
Swiss prot: O43424
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide GluR-delta2 (G860). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: GRID2; GLURD2; GluD2; GluR delta-2 subunit; Glutamate receptor ionotropic; delta-2
Additional info: This peptide can be used with studies using BS3029 GluR-delta2 (G860) pAb.

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