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HCN2 (E521) pAb

HCN2 (E521) pAb

Cat no: BS3372


Supplier: Bioworld Technology, Inc.
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Hyperpolarization-activated, cyclic nucleotide-binding channels (HCN) are voltage-gated cation channels that are activated by direct binding of intracellular cyclic nucleotides. The HCN family consists of four members (HCN1-4), each with a core transmembrane segment domain and a carboxy-terminal 120 amino-acid cyclic nucleotide-binding domain motif. HCN channels are expressed in the brain, heart, thalamus and testis. The pacemaker properties of HCN channels contribute to spontaneous rhythmic activity in the brain and heart. The genes encoding human HCN1 and HCN2 map to chromosomes 5 and 19p13.3, respectively. The genes encoding HCN3 and HCN4 map to chromosomes 1q21.3 and 15q24-q25, respectively.
Catalogue number: BS3372
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: Q9UL51
Dilutions: WB: 1:500~1:1000
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 490-541 of Human HCN2.
Species: HCN2 (E521) pAb detects endogenous levels of HCN2 protein.
Molecular weight: ~ 100 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: HCN2; BCNG-2; BCNG2; HAC-1
Additional info: For research use only, not for use in diagnostic procedure.

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