IL1R2, ID (IL1R2, IL1RB, Interleukin-1 receptor type 2, CD121 antigen-like family member B, CDw121b, IL-1 type II receptor, Interleukin-1 receptor beta, Interleukin-1 receptor type II, CD121b, Interleukin-1 receptor type 2, membrane form, Interleukin-1 re

The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Two alternatively spliced transcript variants encoding the same protein have been reported.\n\nApplications:\nSuitable for use in Western Blot, ELISA\n\nRecommended Dilution:\nELISA: 1:1,000\nWestern Blot: 1:100-500\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Do not freeze R-Phycoerythrin conjugates. Light sensitive. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

036990-PE

Size

200ul

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.2. Contains ~0.09% sodium azide. Conjugated to R-Phycoerythrin (R-PE).

P Type

Pab

Purity

Purified by Protein A affinity chromatography.

Isotype

IgG

References

Giroux, S., et al. Bone 47(5):975-981(2010)\nRomero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :\nBailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)\nChen, C., et al. Rheumatol. Int. (2010) In press :\nSchuurhof, A., et al. Pediatr. Pulmonol. 45(6):608-613(2010)

Additional Info

Human

Alternative Names

IL1R2, IL1RB, Interleukin-1 receptor type 2, CD121 antigen-like family member B, CDw121b, IL-1 type II receptor, Interleukin-1 receptor beta, Interleukin-1 receptor type II, CD121b, Interleukin-1 receptor type 2, membrane form, Interleukin-1 receptor type 2, soluble form