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Integrin, beta7

Cat no: I7661-45A

Integrin, beta7

Integrin beta7 is an adhesion molecule belonging to the integrin beta chain family. It forms heterodimers with the alpha subunit, most notably the integrin alpha4 and alphaE subunits, functioning to mediate migration and homing of lymphocytes to the gut-associated lymphoid tissue (GALT). The heterodimer formed with alpha4, alpha4, beta 7 is specifically involved in the homing and migration of lymphocytes to the gut, while alphaE beta7 is involved in the binding of T lymphocytes to epithelial cells and is induced by TGF beta1. Integrin beta7 has been observed in several different leukocyte lines.\n\nApplications: \nSuitable for use in Flow Cytometry, Immunoprecipitation, Immunohistochemistry. Other applications not tested. \n\nRecommended Dilution:\nFlow Cytometry: 1ug/ml \nOptimal dilutions to be determined by the researcher.\n\nPositive Control:\nHuman peripheral blood mononuclear cells (PBMC's).\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

I7661-45A

Size

100ug

Applications

FC, IHC, IP

Reactivities

Hum

Form

Supplied as a liquid in PBS, 0.1M Tris-Glycine, pH 7.4, 150mM sodium chloride, 0.05% sodium azide.

P Type

Mab

Purity

Purified by ammonium sulfate precipitation.

Isotype

IgG

Additional Info

Recognizes human Integrin beta-7.

Read more on Supplier website

Applications

ELISA

Reactivities

Hum

More info

Applications

IF

Hosts

Mouse

More info

Applications

ELISA, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, IHC, WB

Hosts

Mouse

More info

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

More info

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