JMJD6 (N-terminus) mAb

Cells undergoing apoptosis lose the asymmetry of plasma membrane phospholipids, and phosphatidylserine is exposed on the outer surface of the membrane. The phosphatidylserine receptor (PSR) specifically recognizes phosphatidylserine and this binding triggers the phagocytosis of apoptotic cells by either macrophages or dendritic cells. PSR is expressed on the surface of macrophages, fibroblasts, and epithelial cells, and it has been detected in high levels in heart, skeletal muscle, and kidney tissues and is extensively glycosylated. The mammalian phosphatidylserine receptor displays significant homology to Caenorhabditis elegans and Drosophila melanogaster proteins, which suggests that PSR has been conserved throughout phylogeny.

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SPECIFICATIONS

Catalog Number

MB0100

Size

100ug/100ul

Applications

WB

Hosts

Mouse

Reactivities

Hum

Form

liquid

Purity

The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Antigen

Synthetic peptide, corresponding to the N-terminus of Human JMJD6.

Species

This antibody detects endogenous levels of JMJD6 and does not cross-react with related proteins

Dilutions

WB: 1:1000\nICC: 1:100~200

Swiss Prot

Q6NYC1

Storage Temp

Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.

Concentration

1ug/ul

Storage Buffer

1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Additional Info

For research use only, not for use in diagnostic procedure.

Molecular Weight

Predicted band size:46KDa \nObserved band size:62KDa

Alternative Names

PSR; PTDSR; PTDSR1; KIAA0585; jumonji domain containing 6; Lysyl-hydroxylase JMJD6; Phosphatidylserine receptor; PTDSR; KIAA0585; Histone arginine demethylase JMJD6; JmjC domain-containing protein 6; PSR; Peptide-lysine 5-dioxygenase JMJD6; Protein PTDSR