LILRA5, NT (LILRA5, ILT11, LILRB7, LIR9, Leukocyte immunoglobulin-like receptor subfamily A member 5, CD85 antigen-like family member F, Immunoglobulin-like transcript 11, Leukocyte immunoglobulin-like receptor 9, CD85f)

The protein encoded by this gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family. LIR family members are known to have activating and inibitory functions in leukocytes. Crosslink of this receptor protein on the surface of monocytes has been shown to induce calcium flux and secretion of several proinflammatory cytokines, which suggests the roles of this protein in triggering innate immune responses. This gene is one of the leukocyte receptor genes that form a gene cluster on the chromosomal region 19q13.4. Four alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq].\n\nApplications:\nSuitable for use in Western Blot, ELISA\n\nRecommended Dilution:\nELISA: 1:1,000\nWestern Blot: 1:100-500\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

037775

Size

200ul

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

P Type

Pab

Purity

Purified by Protein A affinity chromatography.

Isotype

IgG

References

Mosbruger, T.L., et al. J. Infect. Dis. 201(9):1371-1380(2010)\nJones, D.C., et al. Eur. J. Immunol. 39(11):3195-3206(2009)\nShiroishi, M., et al. J. Biol. Chem. 281(28):19536-19544(2006)\nBorges, L., et al. Blood 101(4):1484-1486(2003)\nWende, H., et al. Immunogenetics 51 (8-9), 703-713 (2000) :

Additional Info

Human

Alternative Names

LILRA5, ILT11, LILRB7, LIR9, Leukocyte immunoglobulin-like receptor subfamily A member 5, CD85 antigen-like family member F, Immunoglobulin-like transcript 11, Leukocyte immunoglobulin-like receptor 9, CD85f