Melanoma Associated Antigen (Melanoma-associated Antigen, MAA)

The antigen detected by this antibody is found to be associated with the adhesion, spreading and motility of human cultured melanoma cells.\n\nApplications:\nSuitable for use in Immunohistochemistry. Other applications not tested.\n\nRecommended Dilution:\nImmunohistochemistry (Frozen): 1:5-1:10 diluted in PBS. Stain by regular immunoperoxidase and immunofluorescence tests. Reacts preferentially with melanoma cells in frozen tissue sections.\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

M2869-03E

Size

1ml

Applications

IF, IHC

Hosts

Mouse

Form

Supplied as a liquid, 0.1% sodium azide.

P Type

Mab

Purity

Supernatant

Isotype

IgG1

References

1. de Vries, J.E., et al., 1986, Int. J. Cancer, 38, 465.

Additional Info

Recognizes the Melanoma Associated Antigen, a molecular complex consisting of two bands with MW of 150kD and 90kD respectively (reduced 4 subunits 120kD, 95kD, 29kD and 25kD). Reacts strongly with melanoma cells derived from cell lines and short term cultures. Reacts with a proportion of naevi and with endothelial cells of small vessels.