MYST-2 (Histone Acetyltransferase MYST2, Histone Acetyltransferase KAT7, Histone Acetyltransferase Binding to ORC1, Lysine Acetyltransferase 7, MOZ, YBF2/SAS3, SAS2 and TIP60 Protein 2, KAT7, HBO1, HBOa, MYST2) (HRP)

KAT7/Hbo1/MYST2 is a member of the MYST histone acetyltransferae family which acetylates both histone H3 and H4 and is involved in the regulation of DNA replication. The initiation of DNA replication is tightly regulated in eukaryotic cells to ensure that the genome is precisely duplicated once per cell cycle. This is accomplished by controlling the pre-replicative complex. KAT7/Hbo1/MYST2 is a positive regulatory factor for prereplicative complex assembly.\n\nApplications:\nSuitable for use in ELISA and Western Blot. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Labeled with horseradish peroxidase (HRP). Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. HRP conjugates are sensitive to light.

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SPECIFICATIONS

Catalog Number

029210

Size

50ug

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

Form

Supplied as a liquid in PBS. Labeled with horseradish peroxidase (HRP).

P Type

Pab

Purity

Purified by ammonium sulfate precipitation.

Isotype

IgG

References

1. \"Histone acetyltransferase HBO1 interacts with the ORC1 subunit of the human initiator protein.\"Iizuka M., Stillman B.J. Biol. Chem. 274:23027-23034 (1999). 2. \"Androgen receptor interacts with a novel MYST protein, HBO1.\"Sharma M., Zarnegar M., Li X., Lim B., Sun Z.J. Biol. Chem. 275:35200-35208 (2000). 3. \"Cloning and identifying histone acetyltransferase HBOa.\"Jian J., Guangtao L., Guangwei D., Yan Z., Jianhe C., Jiangang Y., Boqin Q.

Additional Info

Recognizes human MYST-2.