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PECI, aa1-364, Recombinant, Human (Delta(3),delta(2)-enoyl-CoA Isomerase, Diazepam-binding Inhibitor-related Protein 1, D3,D2-enoyl-CoA Isomerase, Dodecenoyl-CoA Isomerase, DRS1, DRS-1, HCA88, Hepatocellular Carcinoma-associated Antigen 88, KIAA0536, pECI

Cat no: P3130-39

PECI, aa1-364, Recombinant, Human (Delta(3),delta(2)-enoyl-CoA Isomerase, Diazepam-binding Inhibitor-related Protein 1, D3,D2-enoyl-CoA Isomerase, Dodecenoyl-CoA Isomerase, DRS1, DRS-1, HCA88, Hepatocellular Carcinoma-associated Antigen 88, KIAA0536, pECI

PECI, also referred to as DRS1, ACBD2 or HCA88, is a protein that localizes to the peroxisomal matrix and contains one ACB (acyl-CoA-binding) domain. This protein is expressed abundantly in liver, heart and skeletal muscle. It functions to catalyze the isomerization of both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species, playing an important role in the b-oxidation of unsaturated fatty acids. \n\nSource:\nRecombinant corresponding to aa1-364 of human PECI 6x his tagged, expressed in E.coli. \n\nAA Sequences: \nMGSSHHHHHH SSGLVPRGSH MNRTAMRASQ KDFENSMNQV KLLKKDPGNE VKLKLYALYK QATEGPCNMP KPGVFDLINK AKWDAWNALG SLPKEAARQN YVDLVSSLSP SLESSSQVEP GTDRKSTGFE TLVVTSEDGI TKIMFNRPKK KNAINTEMYH EIMRALKAAS KDDSIITVLT\nGNGDYYSSGN DLTNFTDIPP GGVEEKAKNN AVLLREFVGC FIDFPKPLIA VVNGPAVGIS VTLLGLFDAV YASDRATFHT PFSHLGQSPE GCSSYTFPKI MSPAKATEML IFGKKLTAGE ACAQGLVTEV FPDSTFQKEV WTRLKAFAKL PPNALRISKE VIRKREREKL HAVNAEECNV LQGRWLSDEC TNAVVNFLSR KSKL\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20 degrees C. Aliquots are stable for at least 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

P3130-39

Size

100ug

Form

Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 10% glycerol.

Purity

~95% (SDS-PAGE).

References

1. Dongyan Zhang,et al. (2002) J. Biol. Chem. 277: 9127-9132.

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