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Pepsinogen II, Human

Cat no: P3272-08M

Pepsinogen II, Human

Pepsinogen II or pepsinogen C belongs to a group of aspartic proteinase zymogens (inactive form) that are activated in the acid pH of stomach to active enzyme pepsin. Pepsinogen II (PG II) is produced by chief cells and mucus neck cells of gastric mucosa, pyloric glands in the antrum and Brunner's glands in the proximal duodenum. Serum concentration of PG II reflects the histological status of gastric mucosa. The ratio of concentration of PGI to PGII in serum of normal subjects is about 4:1. The PGI/PGII ratio decreases linearly with increasing grade of atrophic gastritis in the corpus. The ratio is < 2.5 when the atrophic gastritis is advanced (moderate or severe) in the gastric corpus.\n\nSource:\nHuman Pepsinogen II, from human gastric mucosa.\n\nStorage and Stability:\nMay be stored at 4 degrees C. For long-term storage, aliquot and store at 4 degrees C. Do not freeze. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

P3272-08M

Size

100ug

Form

Supplied as a liquid in 0.02M potassium phosphate, pH 7.0, 0.15M sodium chloride. No preservative added.

Purity

Purified. ~98% (SDS-PAGE).

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Applications

ELISA

Reactivities

Hum

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Applications

IF

Hosts

Mouse

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Applications

ELISA, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, IHC, WB

Hosts

Mouse

More info

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

More info
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