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Peroxiredoxin 3 (Antioxidant Protein 1, PRDX3, Thioredoxin Dependent Peroxide Reductase) Recombinant, Human

Cat no: P3352-20

Peroxiredoxin 3 (Antioxidant Protein 1, PRDX3, Thioredoxin Dependent Peroxide Reductase) Recombinant, Human

Peroxiredoxin 3 (Antioxidant Protein 1, PRDX3, Thioredoxin Dependent Peroxide Reductase) is a protein with antioxidant function and is localized in the mitochondrion. The gene encoding this protein shows significant nucleotide sequence similarity to the gene coding for the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase. Expression of this gene product in E. coli deficient in the C22-subunit gene rescued resistance of the bacteria to alkylhydroperoxide. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologues suggest that these genes consist of a family that is responsible for regulation of cellular proliferation, differentiation, and antioxidant functions. \n\nSpecies: Homo sapiens\n\nSource: E. coli\n\nPrimary Sequence (aa): 256\n\nDomain (aa): Full-length\n\nTag/Fusion Partner: T7 Tag\n\nApplications: Suitable for use in ELISA as an Antigen, Ligand, or Assay Standard. Other applications not tested.\n\nQuality Control: SDS-PAGE Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage, aliquot to avoid repeated freezing and thawing and freeze at -70 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquots are stable for at least 12 months. \n\nImportant note: This recombinant enzyme has NOT been tested with regard to biological activity.

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SPECIFICATIONS

Catalog Number

P3352-20

Size

50ug

Applications

ELISA

Form

Supplied as a liquid in PBS, pH 7.2. No preservative added.

Purity

Highly purified

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