Prasugrel Hydrochloride (2-[2-(Acetyloxy)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl]-1-cyclopropyl-2-(2-fluorophenyl)ethanone Hydrochloride; CS 747; Effient; LY 640315)

A novel antiplatelet agent; it is a third-generation thienopyridine. Antiplatelet agent Prasugrel showed greater platelet inhibition and decreased incidence of ischemic events than Clopidogrel but may induce increased incidence of bleeding in patients.\n\nMethod for Determining Identity:\nProton NMR Spectroscopic and Mass Spectrometric Analysis\n\nRelated Substances: \nTotal(same/less than)1.0%\nIndividual(same/less than)0.5%\n\nLoss on Drying:\n(same/less than)0.5%\n\nResidue on Ignition:\n(same/less than)0.1%\n\nHeavy Metals:\n(same/less than)0.002%\n\nStorage and Stability: \nMay be stored at RT for short-term only. Long-term storage is recommended at -20 degrees C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.\n\nToxicity and Hazards:\nDue to the potential danger associated with the use of some of United States Biological biochemicals, all products should be handled by qualified personnel only, trained in laboratory procedures, and familiar with potential hazards. Information is not available on the possible hazards of many experimental compounds. The absence of a warning must not be interpreted as indication of safety.

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SPECIFICATIONS

Catalog Number

P5620

Size

100mg

Form

Supplied as a light yellow or off white crystalline powder.

Purity

~90%

References

1. Von Beckerath, N., et al.: Circulation, 112, 2946 (2005). 2. Jernberg, T., et al.: Eur. Heart J., 27, 1166 (2006). 3. Farid, N., et al.: Drug Metab. Dispos., 35, 1096 (2007). 4. Farid, N., et al.: Clin. Pharmacol. Ther., 81, 735 (2007). 5. Jakubowski, J., et al.: J. Cardiovasc. Pharmacol., 49, 167 (2007). 6. Wiviott, S., et al.: N. Engl. J. Med., 357, 2001 (2007).

Alternative Names

2-[2-(Acetyloxy)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl]-1-cyclopropyl-2-(2-fluorophenyl)ethanone Hydrochloride; CS 747; Effient; LY 640315