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PRL, Recombinant, Human (Prolactin, LTH, Mammotropin, Luterotropic Hormone, Lutetropin)

Cat no: 142970

PRL, Recombinant, Human (Prolactin, LTH, Mammotropin, Luterotropic Hormone, Lutetropin)

Prolactin (PRL) is a hormone that is made and secreted by the pituitary gland and acts in an endocrine, paracrine and autocrine manner. The prolactin receptor is expressed on many cell types and is linked to JAK kinase signaling pathways. PRLпїЅs primary function is to regulate lactation, but it is known to have many other regulation functions. These functions include roles in the immune system, cell growth, apoptosis, and differentiation. \n\nSource:\nRecombinant protein corresponding to 200aa from human Prolactin expressed in E.coli. \n\nMolecular Weight: \n~23kD \n\nEndotoxin:\n(same/less than)1EU/ug (LAL)\n\nBiological Activity:\nThe activity is determined by the ability to stimulate proliferation of NB2-11 cells and is typically <1ng/ml.\n\nAA Sequence:\nMLPICPGGAA RCQVTLRDLF DRAVVLSHYI HNLSSEMFSE FDKRYTHGRG FITKAINSCH TSSLATPEDK EQAQQMNQKD FLSLIVSILR SWNEPLYHLV TEVRGMQEAP EAILSKAVEI EEQTKRLLEG MELIVSQVHP ETKENEIYPV WSGLPSLQMA DEESRLSAYY NLLHCLRRDS HKIDNYLKLL KCRIIHNNNC\n\nStorage and Stability: \nLyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with sterile dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Reconstituted product is stable for 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

142970

Size

10ug

Form

Supplied as a lyophilized powder in 10mM Na2PO4, pH 7.5. Reconstitute with sterile dH2O.

Purity

~97% (Reducing and non-reducing SDS-PAGE)

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