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Prostaglandin D2 Synthase (PTGDS) Recombinant, Human, aa23-190, His-tag

Cat no: P9053-24M

Prostaglandin D2 Synthase (PTGDS) Recombinant, Human, aa23-190, His-tag

Prostaglandin-H2 D-isomerase, also known as PTGDS, is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system. PTGDS is the most abundant protein in the cerebral spinal fluid and recent evidence suggests that PTGDS acts as a beta-amyloid chaperone and may have a role in the deposition of Ab plaques in Alzheimer

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SPECIFICATIONS

Catalog Number

P9053-24M

Size

50ug

Form

Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 1mM DTT, 1mM EDTA, 0.1M sodium chloride, 30% glycerol.

Purity

~90% (SDS-PAGE)

References

1. Hoffmann A., et al. (1993) J Neurochem. 61(2):451-6. 2. Giacomelli S., et al. (1996) Biochem Biophys Acta. 1310(3):269-76.

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