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Prostate Specific Gene-1, Recombinant, Human (HPG-1)

Cat no: P9054-77H

Prostate Specific Gene-1, Recombinant, Human (HPG-1)

Human Prostate-Specific Gene-1 (HPG-1) product is a recently discovered membrane-anchored protein of approximately 15 kD. It was detected exclusively in the prostate (19 different tissues were tested). Antisense-oligonicleotide inhibition of HPG-1 expression inhibited the growth of one prostate cancer cell line (LNCaP) significantly (86%). HPG-1 might be a novel diagnostic and/or therapeutic target.\n\nDescription: \nRecombinant HPG-1 is a 16kD recombinant fusion protein consisting of 127 amino acid residues of the human PG-1 and 9 additional amino acid residues of the His-Tag (bold). MKHHHHHHHM IKKNLKKLGI EETYLNIIKA IYDRPTASIQ KTENLSTKTG TSQEYHLSPL WFYIVLEILA STIRQEKNLK DIHTEKEEVK LSLFADAMIL YLKKPNDSTR KLLELIKKIH SSCRIKINIH FAFCSQ.\n\nSpecificity: \nThe amino acid sequence of the recombinant human PG-1 is 100% homologous to the amino acid sequence of the HPG-1.\n\nApplications:\nWestern blotting, ELISA\n\nReconstitution: \nAdd 0.2 ml of dH2O and let the lyophilized pellet dissolve completely. For conversion into higher pH value, we recommend intensive dilution by relevant buffer to a concentration of 10 g/ml. In higher concentrations the solubility of this antigen is limited.\n\nStability/Shelf Life: \nStore lyophilized protein at -20 degrees C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4 degrees C for a limited period of time. The lyophilized protein remains stable until the expiry date when stored at -20 degrees C.

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SPECIFICATIONS

Catalog Number

P9054-77H

Size

2ug

Form

Supplied as a lyophilized powder in 0.05M MES buffer, pH 6.5.

Purity

(same/more than) 95% (SDS-PAGE); Ni-NTA affinity chromatography

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