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TBX18 (T-box Transcription Factor TBX18, T-box Protein 18)

Cat no: T1848-42A

TBX18 (T-box Transcription Factor TBX18, T-box Protein 18)

TBX18 is a 607aa 65kD protein that is a member of the T-box family of developmentally expressed transcription factors. It is developmentally expressed in the anterior portion of the head, somites and limb buds. It is expressed on pluripotent progenitors in the developing epicardium where it is required for formation of the cardiac AV node, and can also contribute to fibroblast and smooth muscle formation. Within the region used as an immunogen, human TBX18 shares 93% aa identity with mouse and rat TBX18.\n\nApplications:\nSuitable for use in Immunocytochemistry. Other applications not tested.\n\nRecommended Dilution:\nImmunocytochemistry: 8-25ug/ml\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nLyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

T1848-42A

Size

100ug

Applications

ICC

Hosts

Mouse

Reactivities

Hum

Form

Supplied as a lyophilized powder in PBS, trehalose. Reconstitute with sterile PBS to 0.5mg/ml.

P Type

Mab

Purity

Purified by Protein A/G affinity chromatography.

Isotype

IgG2B

Additional Info

Recognizes human TBX18. Does not react with recombinant human TBX2, 3, 5, 6, 20, or rhT-bet.

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