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Tubulin (gamma) (F414) pAb

Tubulin (gamma) (F414) pAb

Cat no: BS1483

Supplier: Bioworld Technology, Inc.
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TUB4, the gene for Saccharomyces cerevisiae (gamma)-Tubulin, encodes a 473 amino acid structural protein that localizes to the spindle pole body. (gamma) Tubulin, an essential protein for cell growth, organizes microtubule arrays in the nucleus and cytoplasm. (gamma) Tubulin-depleted cells fail to form functional spindles and arrest during nuclear division. (gamma) Tubulin associates with spindle body components Spc97 and Spc98 to form the (gamma) Tubulin complex. The budding yeast (gamma) Tubulin complex contains one molecule each of Spc97 and Spc98 and two molecules of (gamma) Tubulin. In the SPB, Spc110 binds Spc97 and Spc98 of the (gamma) Tubulin complex. 2D gel analysis indicates five isoforms of (gamma) Tubulin. The phosphorylation of (gamma) Tubulin at Tyr 445 plays a regulatory role in microtubule formation. The incidence rate for this phosphorylation event peaks during G1.
Catalogue number: BS1483
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: P23258
Dilutions: WB: 1:500~1:1000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 380-430 of Human Tubulin (gamma).
Species: Tubulin (gamma) (F414) pAb detects endogenous levels of Tubulin (gamma) protein.
Molecular weight: ~55 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: gamma Tubulin - Centrosome Marker; Gamma-1-tubulin; Gamma-tubulin complex component 1; GCP-1; TUBG1; 7283; TUBG1; 191135; P23258; TUBG; 27175; TUBG2; 605785; Q9NRH3; MGC131994;
Additional info: For research use only, not for use in diagnostic procedure.

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