Home  >  Products  >  UCP1 (Mitochondrial Brown Fat Uncoupling Protein 1, UCP 1, Solute Carrier Family 25 Member 7, Thermogenin, SLC25A7, UCP)

UCP1 (Mitochondrial Brown Fat Uncoupling Protein 1, UCP 1, Solute Carrier Family 25 Member 7, Thermogenin, SLC25A7, UCP)

Cat no: U1620-08E


Supplier: United States Biological
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UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:128,000 Western Blot: 0.1-1ug/ml, observed in human adipose lysates on ~35kD bands Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: U1620-08E
Reactivities: Human, Mouse, Rat, Canine
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
References: 1. Ishigaki Y, Katagiri H, Yamada T, Ogihara T, Imai J, Uno K, Hasegawa Y, Gao J, Ishihara H, Shimosegawa T, Sakoda H, Asano T, Oka Y. Dissipating excess energy stored in the liver is a potential treatment strategy for diabetes associated with obesity. Diabetes. 2005 Feb;54(2):322-32.
Additional info: Recognizes human UCP1. Species sequence homology: Canine, mouse and rat.

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