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ULK1 (Serine/Threonine-protein Kinase ULK1, Unc-51-like Kinase 1, KIAA0722)

Cat no: U1500-70D

ULK1 (Serine/Threonine-protein Kinase ULK1, Unc-51-like Kinase 1, KIAA0722)

ULK1 is the mammalian homologue of a C. elegans protein (uncordinated51) involved in neurite growth. The protein is also a homologue of the yeast atg1 protein, a kinase involved in autophagy. The protein constitutes a novel sub-family of serine/threonine kinases. The autophagic role of the protein may be directly linked to neurite growth. The protein is ubiquitously expressed in adult human tissues such as skeletal muscle, heart, pancreas, brain, placenta, liver, kidney, and lung. Both FISH and RH mapping confirmed the regional localization of Ulk1 gene to human chromosome 12q24.3. The protein is also important for axon formation in cerebellar granule neuron and in neurite extension of cerebellar granule cells.\n\nApplications:\nSuitable for use in ELISA. Other applications not tested.\n\nRecommended Dilution:\nELISA: 1:100-1:1000\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

U1500-70D

Size

100ul

Applications

ELISA

Hosts

Rabbit

Reactivities

Hum

Form

Supplied as a liquid, 0.025% sodium azide, 50% glycerol.

P Type

Pab

Purity

Serum

Isotype

IgG

References

1. Kuroyanagi, H. et al. Genomics. 51:76-85 (1998). 2. Nagase, T. et al. DNA Res. 5:277-86 (1999).

Additional Info

Recognizes human ULK1. Species sequence homology: mouse, rat, canine.

Read more on Supplier website

Applications

FC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC

Hosts

Mouse

Reactivities

Hum

More info
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