UII-R, initially named GPR14, is a Urotensin Receptor that binds urotensin-II (U-II) and regulates cardiovascular function. Urotensin-II receptor has been reported to be expressed at high levels in the heart and pancreas and also in artery and smooth muscle. Low transcript levels have been identified in brain, particularly in thalamus, superior occipital gyrus, and substantia nigra. ESTs have been isolated from fetal, melanocyte/uterus/fetal heart, and ovarian thecoma fibroma libraries.
Applications:
Suitable for use in Immunohistochemistry. Other applications not tested.
Recommended Dilution:
Immunohistochemistry (paraffin): 7-13ug/ml
Optimal dilutions to be determined by the researcher.
Positive Control:
Human Pancreas, Islet of Langerhans
Storage and Stability:
May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.