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Virginiamycin S1 (Staphylomycin S, PA 114B2, Antibiotic 899, Antibiotic PA 114B2, Antibiotic 1745Z3B, Factor S )

Cat no: V2122-81

Virginiamycin S1 (Staphylomycin S, PA 114B2, Antibiotic 899, Antibiotic PA 114B2, Antibiotic 1745Z3B, Factor S )

Virginiamycin S1 is one of a family of depsipeptide antibiotic co-produced with ostreogrycin A and used as a synergistic mixture. Virginiamycin S1 also known as Staphylomycin S and Factor S, among other synonyms were discovered independently and named by several groups leading to considerable confusion in the literature. Virginiamycin S1 acts a synergist binding to the conformational change induced by ostreogrycin A of the peptidyl transferase centre of the 50S ribosome. Virginiamycin S1 differs from virginiamycin B in lacking the dimethylamino moiety on the phenyl ring.\n\nSoluble in ethanol, methanol, DMF or DMSO. Limited water solubility

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SPECIFICATIONS

Catalog Number

V2122-81

Size

5mg

Form

White solid

Purity

> 99% by HPLC

References

1. The structures of the minor components of virginiamycin S. Vanderhaeghe, H. et al., Tet. Lett. 1971, 2687 2. Virginiamycin: nomenclature. Crooy P. and De Neys R. J. Antibiot. 1972, 25, 371. 3. A new species of Streptomyces producing virginiamycin family antibiotics. Ogata, K. et al., J. Antibiot. 1978, 31, 1313.

Alternative Names

Staphylomycin S, PA 114B2, Antibiotic 899, Antibiotic PA 114B2, Antibiotic 1745Z3B, Factor S

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