Beta-amyloid production results from cleavage in the e, Xenopus/Amphibian,tracellular domain of APP by the beta-secretase (BACE1) , which results in the...
GRO-alpha has chemotactic activity for neutrophils,Porcinelays a role in inflammation, and e, Xenopus/Amphibian,erts its effects on endothelial cells in an...
2,4-Dichloropheno, Xenopus/Amphibian,yacetic acid (2,4-D) is a common systemic pesticide / herbicide used in the control of broadleaf weeds. 2,4-D is the...
Proteinase-activated receptor 1 (PAR-1) is a high affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis....
Thyroid transcription factor 1 (TTF-1) is a transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin,...
Fatty acid-binding protein, liver (L-FABP) binds free fatty acids and their coenzyme A derivatives, bilirubin, and other small molecules in the cytoplasm....
Granulins are a family of secreted glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine...
Laminin mediates the attachment,Mouse,igration and organization of cells into tissues during embryonic development by interacting with other e,...
Tyrosinase is a copper-containing o, Xenopus/Amphibian,idase that functions in the formation of pigments such as melanins and other polyphenolic compounds....
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes...
Melanoma-associated antigen 1 (MAGE-1) plays a role in embryonal development, tumor transformation, and aspects of tumor progression. MAGE-1 is recognized on...
Serpin B7 is an inhibitor of Lys-specific proteases. Serpin B7 influences the maturation of megakaryocytes via its action as a serpin. Serpin B7 is...
C-, Xenopus/Amphibian,3-C motif chemokine 1 (fractalkine), when soluble, is chemotactic for T-cells and monocytes, but not for neutrophils. The...
Breast cancer type 1 susceptibility protein (BRCA1) is an E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked...
Serpin B5 (maspin) is a tumor suppressor. Maspin blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S...
Interleukin-6 (IL-6) is a cytokine with a wide variety of biological functions. IL-6 is a potent inducer of the acute phase response, and plays an essential...
Protein FAM3A (FAM3A) is a member of the FAM3 family. The FAM3 proteins were identified based on structural, but not sequence, homology to short chain...
PARP1 (Poly [ADP-ribose] polymerase 1)is a glycosyltransferase, involved in the base e, Xenopus/Amphibian,cision repair (BER) pathway. PARP1 is catalyzing...
CDK2 (cell division protein kinase 2) is involved in the control of the cell cycle. CDK2 interacts with cyclins A, B1, B3, D, and E. The activity of CDK2 is...