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FGFR4 is a receptor for acidic fibroblast growth factor but does not bind to basic fibroblast growth factor.
FGFR2 is a receptor for acidic and basic fibroblast growth factors. Defects in FGFR2 are the cause of numerous craniofacial abnormalities such as Crouzon,...
EphA2 is a receptor for members of the ephrin-A family. EphA2 binds to ephrin-A1, A3, A4 and A5.
Dnmt3A is required for genome wide de novo methylation and is essential for development.
Dnmt1 methylates CpG residues preferentially on hemimethylated DNA for maintaining methylation patterns established during development.
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a 19-kDa prohormone processed into PACAP-related peptide (PRP-48),PorcineACAP-27 and PACAP-38....
Actins are highly conserved proteins involved in cell motility that are ubiquitously e, Xenopus/Amphibian,pressed in eukaryotic cells. There are 3 main actin...
Testicular receptor 2 (TR2) is a member of the orphan nuclear receptor family. TR2 is widely e, Xenopus/Amphibian,pressed at a low level throughout the adult...
Cyclin-dependent kinase 1 (CDK1) plays a key role in the control of the eukaryotic cell cycle. CDK-1 is required in higher cells for entry into S-phase and...
SYT1 (Synaptotagmin) is widely regarded as the primary calcium sensor for synaptic vesicle e, Xenopus/Amphibian,ocytosis. Synaptotagmin can be phosphorylated...
The 5'-nucleotidase cytosolic II (NT5C2) has a critical role in the maintenance of a constant composition of intracellular purine/pyrimidine nucleotides in...
Glutamate [NMDA] receptor subunit epsilon-2 (N-methyl D-aspartate receptor subtype 2B receptor or NMDA NR2B) is a NMDA receptor subtype of glutamate-gated...
Tumor necrosis factor alpha (TNF-alpha) is a cytokine that binds to the TNF-R1 and TNF-R2 receptors. TNF-alpha is mainly secreted by macrophages and induces...
The nociceptin receptor (KOR-3) is the receptor for the neuropeptide nocipeptin/orphanin FQ. KOR-3 has a potential role in modulating a number of brain...
Nociceptin is the ligand of the opioid receptor-like receptor (OPRL1). Nociceptin acts as a transmitter in the brain by modulating nociceptive and locomotor...
HSP-90 beta (Heat shock protein HSP 90-beta) is a homodimer with ATPase activity and functions as a molecular chaperone. HSP-90 beta is involved in the...
Aquaporin-2 (AQP-2) forms a water specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby...
Ubiquitin C-terminal hydrolase 1 (UCHL1) cleaves ubiquitin from other molecules. Genetic knockout of UCHL1 in mice results in a motor neuron degeneration...
Tyrosine hydro, Xenopus/Amphibian,ylase (TH) catalyzes the conversion of tyrosine to L-DOPA, which is the rate limiting step in the biosynthesis of...
INHA (Inhibin alpha) is a 366 amino acid long (~40kD) protein, regulates endocrin secretion. It is involved in regulating a number of diverse functions such...
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