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RAB10 (Ras-related protein Rab-10) belongs to the RAS superfamily of small GTPases. RAB proteins localize to e, Xenopus/Amphibian,ocytic and endocytic...
Bcl-2 blocks cell death following a variety of stimuli and confers a death-sparing effect to certain hematopoietic cell lines following growth factor...
SMAD3 (Mothers against decapentaplegic homolog 3) is a tumor suppressor protein. SMAD proteins are signal transducers and transcriptional modulators that...
PRDM1/Blimp1 (PR domain zinc finger protein 1) is a repressor of beta-interferon gene e, Xenopus/Amphibian,pression. This action is e,...
ERK1 and ERK2 (E, Xenopus/Amphibian,tracellular signal-regulated kinase 1 and 2) are members of the MAP kinase signal transduction pathway. The activation of...
BDH1 (3-hydro, Xenopus/Amphibian,ybutyrate dehydrogenase, type 1) belongs to the short-chain dehydrogenase/reductase gene family. This protein forms a...
PP-1A (Serine/threonine-protein phosphatase PP1-alpha catalytic subunit) is a 330 amino acid protein (~38 kD). It is essential for cell division, and...
FAK (Focal adhesion kinase) is a 1074 -amino acid protein (~118 kDa). It is a member of the FAK subfamily of protein tyrosine kinases but lacks significant...
Rab25 is a 28 kDa protein, belongs to the small GTP-ase superfamily. Members of the Ras-related superfamily of GTP binding proteins which includes Ras, Rho,...
CHD3 (Chromodomain-helicase-DNA-binding protein 3) is a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin...
NFKB p65 (Nuclear factor NF-kappa-B p65 subunit) is a pleiotropic transcription factor. It is present in almost all cell types and is involved in many...
JAK3 (Janus kinase 3) is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal...
PTEN (Phosphatase and tensin homolog) is a dual-specificity protein phosphatase, dephosphorylating tyrosine-, threonine- and serine-phosphorylated proteins....
WNT1 (Wingless-type MMTV integration site family,Mouse,ember 1.) is member of the WNT signaling pathway. These proteins have been implicated in oncogenesis...
GATA4 (GATA binding protein 4) is a 46 kDa member of the GATA family of zinc-finger transcription factors. Members of this family is involved in the...
PDGFR(B) (Platelet-derived growth factor receptor, beta polypeptide) is a 190 kD cell surface tyrosine kinase receptor for members of the platelet-derived...
AAT (Alpha-1-antitrypsin) is an inhibitor of serine proteases. Although AAT's primary target is elastase, the enzyme has also a moderate affinity for plasmin...
SOD1 (Supero, Xenopus/Amphibian,ide dismutase 1) destroys free radicals which are normally produced within the cells and which are to, Xenopus/Amphibian,ic...
CD18 is a 95-kDa transmembrane protein, integrin beta-2 subunit. It is associated with the integrin ? subunits: CD11a, CD11Bovine, CD11c and CD11d forming...
BRAF (v-raf murine sarcoma viral oncogene homolog B1) is the main effectors recruited by GTP-bound Ras to activate the MEK-MAP kinase pathway. B-Raf contains...
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