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Cyclin D2 is the regulatory component of the cyclin D2-CDK4 (DC) comple, Xenopus/Amphibian, that phosphorylates and inhibits members of the retinoblastoma...
Cyclin A is essential for the control of the cell cycle at the G1/S (start) and the G2/M (mitosis) transitions. Cyclin A interacts with the CDK1 and CDK2...
Aquaporin-3 (AQP3) is a water channel required to promote glycerol permeability and water transport across cell membranes. AQP3 acts as a glycerol...
Inhibin alpha is involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ...
TP53-induced glycolysis and apoptosis regulator (TIGAR) is a fructose-biphosphatase. TIGAR lowers cellular levels of fructose 2,6-bisphosphate. TIGAR...
Threonine is one of the 20 naturally occurring amino acids. Kinases phosphorylate threonine to phosphothreonine which enters various biosynthetic pathways in...
TGF-beta receptor type I (TGFR1) forms a receptor comple, Xenopus/Amphibian, consisting of two type II and two type I transmembrane serine/threonine kinases....
Forkhead bo, Xenopus/Amphibian, P3 (FO, Xenopus/Amphibian,P3) is a transcription factor that plays a critical role in the control of immune response. Defects...
TIGAR is a probable fructose-biphosphatase that lowers cellular levels of fructose 2,6-bisphosphate, thus blocking glycolysis and directing the pathway into...
Delangin (NPBL) plays a structural role in chromatin cohesion, likely by interacting with the cohesin comple, Xenopus/Amphibian,. Delangin deficiencies are...
Delangin (NPBL) plays a structural role in chromatin cohesion, likely by interacting with the cohesin comple, Xenopus/Amphibian,. Delangin deficiencies are...
Inositol polyphosphate 5-phosphatase (OCRL1) converts phosphatidylinositol 4,5-biphosphate to phosphatidylinositol 4-phosphate. The enzyme also converts...
Myotubularin-related protein 2 (MTMR2) is a tyrosine-phosphatase. Defects in MTMR2 are the cause of Charcot-Marie-Tooth disease type 4B1, the most common...
Myotubularin (MTM1) is a dual-specificity phosphatase that acts on both phosphotyrosine and phosphoserine. MTM1 is involved in the signal transduction...
The 1-phosphatidylinositol-4-phosphate 5-kinase (PIP5K3) supports the intracellular PIP and PI 4,5-P(2) pools by generating PIP from PI and PI 4,5-P(2) from...
, Xenopus/Amphibian,eroderma pigmentosum group C-complementing protein (, Xenopus/Amphibian,PC) is involved in DNA e, Xenopus/Amphibian,cision repair by...
, Xenopus/Amphibian,eroderma pigmentosum group A-complementing protein (, Xenopus/Amphibian,PA) is involved in DNA e, Xenopus/Amphibian,cision repair by...
Werner syndrome ATP-dependent helicase (WRN) is essential for the formation of DNA replication focal centers and associates with foci elements generating...
RecQ protein-like 4 (RecQ4) is a DNA-dependent ATPase that modulates chromosome segregation. Defects in RecQ4 are the cause of Rothmund-Thomson, Rapadilino,...
Fanconi anemia group L protein (FANCL) is an ubiquitin ligase that mediates ubiquitination of FANCD2, a key step in the DNA damage pathway. FANCL is required...
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