Type IV collagen (collagen type IV) is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with...
The Myc proto-oncogene protein (c-Myc) participates in the regulation of gene transcription. C-Myc is a transcription factor that binds DNA containing the...
Keratin, type I cytoskeletal 13 (cytokeratin-13) is a type I cytokeratin. Cytokeratin 1 is paired with keratin 4 and found in the suprabasal layers of...
Cytokeratin-7 blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Cytokeratin-7 is involved in the translational regulation of the...
Carcinoembryonic antigen (CEA) is a comple, Xenopus/Amphibian, immunoreactive glycoprotein with a molecular weight of 180,000 comprising 60% carbohydrate....
Cyclin-dependent kinase 7 (Cdk7) is the catalytic subunit of the CDK-activating kinase (CAK) comple, Xenopus/Amphibian,, a serine-threonine kinase. Cdk7...
Cell division control protein 6 homolog (Cdc6) is involved in the initiation of DNA replication. Cdc6 participates in checkpoint controls that ensure DNA...
Cdc25C (Dual specificity phosphatase Cdc25C) is a dosage-dependent inducer in mitotic control. Cdc25C is a tyrosine protein phosphatase required for...
The CD8 antigen is e, Xenopus/Amphibian,pressed on human cytoto, Xenopus/Amphibian,ic/suppressor T-cells, human NK cell subset, cortical thymocyte subset and...
CD4 antigen is found on a T-cell subset (helper/inducer) representing 45% of peripheral blood lymphocytes. CD4 is also present on 80% of thymocytes and at a...
CD3 T-Cell Co-Receptor (CD3) is a protein comple, Xenopus/Amphibian, and is composed of four distinct chains. In mammals, the comple, Xenopus/Amphibian,...
Cathepsin D is an acid protease active in intracellular protein breakdown. Cathepsin D is involved in the pathogenesis of several diseases such as breast...
Apoptosis regulator Bcl-2 (Bcl-2) suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Bcl-2...
B-cell lymphoma/leukemia 10 (Bcl-10) promotes apoptosis,Porcinero-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK. Bcl-10 is an adapter...
BRCA1-associated protein 1 (BAP1) is a deubiquitinating enzyme that plays a key role in chromatin by mediating deubiquitination of histone H2A and HCFC1....
Myosins comprise a family of ATP-dependent motor proteins and are best known for their role in muscle contraction and their involvement in a wide range of...
Follicle-stimulating hormone beta subunit (FSH beta) stimulates the development of follicle and spermatogenesis in the reproductive organs. Defects in FSH...
Lutropin subunit beta (LSH beta) is a heterodimer composed of a common alpha chain and a unique beta chain which confers biological specificity to...
Human prostate-specific antigen (PSA or KLK3) is an important marker for the diagnosis and management of prostate cancer. This is an androgen-regulated...
Hyaluronan synthase 1 (HA synthase 1) plays a role in hyaluronan/hyaluronic acid (HA) synthesis. HA synthase 1 catalyzes the synthesis of...