Suppliers Cayman Chemical Company
CRP is a 224 amino acid protein that is synthesized primarily by hepatocytes, and to a lesser extent adipocytes. CRP plasma levels increase ~1,000-fold in...
The NF-kB/Rel family of transcription factors is comprised of several structurally-related proteins that form homodimers and heterodimers and include...
LDL uptake and its regulation are important therapeutic targets for atherosclerosis and related diseases. Cayman Chemical's LDL Uptake Cell-Based Assay...
Human SIRT1 is the homolog of yeast Sir2 and has been shown to regulate the activity of the p53 tumor suppressor and inhibit apoptosis. Cayman's SIRT1...
XO catalyzes the hydroxylation of hypoxanthine to xanthine and then further catalyzes the oxidation of xanthine to uric acid. When oxidizing NADH, XO...
Three known isoforms of SREBP transcription factors have been characterized: SREBP-1a, SREBP-1c, and SREBP-2. SREBP-1c acts primarily to activate genes...
Glycerol is the backbone of triglycerides and an important intermediate in energy metabolism being involved in both oxidative and synthetic processes. The...
Cayman's Apoptotic Blebs Assay employs a recombinant protein derived from single chain variable fragments (scFv) of an antibody that preferentially binds to...
Glutathione (GSH) is involved in maintenance of protein sulfhydryl reduction status. PSSG may modify the activity of a large number of cell proteins,...
The (gamma)-tocopherol metabolite, (gamma)-CEHC, is produced in the liver by the action of CYP450 enzymes and excreted in urine at levels that exceed all...
Cayman's ERK/MAPK (Phospho-Thr202/Tyr204) Cell-Based Phosphorylation/Translocation Assay provides the tools necessary to study ERK/MAPK phosphorylation and...
The sirtuins represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs) that catalyze a reaction coupling lysine...
p38 MAPK is activated by phosphorylation at Thr180 and Tyr182 in response to both inflammatory cytokines and stress, making it an important enzyme in...
The measurement of TG levels, in conjunction with other lipid assays, are useful in the diagnosis of primary and secondary hyperlipoproteinemia,...
Cayman's FABP4 Ligand Binding Assay provides a simple, reproducible, and sensitive tool for the identification of FABP4 ligands. The assay makes use of a...
Cayman's XTT Cell Proliferation Assay provides an easy to use tool for studying induction and inhibition of cell proliferation in any in vitro model. The...
Cayman's WST-8 Cell Proliferation Assay provides an easy to use tool for studying the induction or inhibition of cell proliferation in any in vitro model....
The Cayman Aspirin(TM) Effect-Detection is a 510K, clinically-approved diagnostic kit for the measurement of 11-dehydro TXB2. It is intended to help...
The identification of ChREBP activators is of great interest for drug discovery. The distinct translocation of the protein from the cytoplasm to the nucleus...
Cayman's In Vitro Angiogenesis Assay uses a one-step model to study regulators of angiogenesis. Cell survival is improved compared to the other assays by use...
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