Glucokinase (also designated hexokinase IV, HXKIV or GCK) plays a key role in the regulation of glucose-induced insulin secretion. GCK is expressed in...
Flotillins belong to a family of lipid raft-associated integral membrane proteins that carry a evolutionarily conserved domain called the prohibitin homology...
ECP (eosinophil cationic protein), also known as RNS3 or RNASE3 (ribonuclease,RNase A family, 3), is a 160 amino acid potent cytotoxic secretory protein that...
Excitatory Amino Acid Transporters (EAATs) are membrane-bound proteins that are localized in glial cells and pre-synaptic glutamatergic nerve endings. EAATs...
E2Fs have been implicated in regulating at least three critical aspects of cell growth: cell cycle entry, differentiation and apoptosis. At present, the...
Carboxypeptidase N (arginine carboxypeptidase or CPN) cleaves basic amino acid residues from the carboxy terminal of peptides and proteins. The enzyme plays...
CTPS (cytidine-5-prime-triphosphate synthase) is a 591 amino acid protein that contains one glutamine amidotransferase type-1 domain and is involved in...
Defects in COX10 are a cause of mitochondrial complex IV deficiency (MT-C4D) [MIM:220110]; also known as cytochrome c oxidase deficiency. A disorder of the...
BRCA 2 is localized to chromosome 13q12 - q13. Loss of heterozygosity of 13q is observed in 25% of sporadic breast tumors, which indicates that BRCA 2 might...
Peropsin is a visual pigment-like protein identified following large-scale sequencing of cDNAs derived from human ocular tissues. Peropsin mRNA is found in...
Three types of opioid receptors have been cloned: mu, delta, and kappa. Opioid receptors are seven transmembrane G-protein coupled receptors. They share a...
Opioid is the term used to designate a group of compounds that are opium-like in their properties. These drugs have effects on perception of pain,...
GPCR GPR136, also known as Opsin 5, is a member of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. This gene belongs to the...
Melanopsin is an opsin-like protein found in the retinal ganglion cells of mammals. Melanopsin is believed to be part of a secondary optical system that...
Opsins, including Encephalopsin, are members of the superfamily of guanine nucleotide-binding protein (G protein)-coupled receptors, which function through...
Voltage-dependent calcium channels are essential for the release of neurotransmitters. Cacna2d1 (calcium channel, voltage-dependent, alpha2/delta subunit 1),...
Dental enamel is a highly mineralized tissue with most of its volume occupied by large, highly organized, hydroxyapatite crystals. This structure is thought...
VEGF is a dimeric glycoprotein with structural homology to PDGF. Several variants of VEGF have been described that arise by alternative mRNA splicing. It has...
Myostatin (GDF8) is expressed uniquely in human skeletal muscle as a 12 kDa mature glycoprotein consisting of 113 amino acid residues and secreted into...