Categories Antibodies
PIK3CA, a PI3/PI4 kinase,Porcinehosphorylates PtdIns,PorcinetdIns4P and PtdIns(4,5)P2 with a preference for PtdIns(4,5)P2. Defects in PIK3CA are associated...
PERK, a Ser/Thr protein kinase,Porcinehosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation and...
PDK4 inhibits the mitochondrial pyruvate dehydrogenase comple, Xenopus/Amphibian, by phosphorylation of the E1 alpha subunit, thus contributing to the...
LRRK2 is involved in the phosphorylation of proteins central to Parkinson disease. Defects in LRRK2 are the cause of Parkinson disease 8 (PARK8).
INSR binds insulin and has a tyrosine protein kinase activity. The short isoform has a higher affinity for insulin. The receptor mediates the metabolic...
IGF1R binds insulin-like growth factor 1 (IGF1) with high affinity and IGF2 with low affinity. The receptor has a tyrosine protein kinase activity necessary...
Synoviolin (SYVN1) acts as an E3 ubiquitin-protein ligase which accepts ubiquitin specifically from endoplasmic reticulum-associated UBC7 E2 ligase and...
FGFR4 is a receptor for acidic fibroblast growth factor but does not bind to basic fibroblast growth factor.
FGFR2 is a receptor for acidic and basic fibroblast growth factors. Defects in FGFR2 are the cause of numerous craniofacial abnormalities such as Crouzon,...
EphA2 is a receptor for members of the ephrin-A family. EphA2 binds to ephrin-A1, A3, A4 and A5.
Dnmt3A is required for genome wide de novo methylation and is essential for development.
Dnmt1 methylates CpG residues preferentially on hemimethylated DNA for maintaining methylation patterns established during development.
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a 19-kDa prohormone processed into PACAP-related peptide (PRP-48),PorcineACAP-27 and PACAP-38....
Actins are highly conserved proteins involved in cell motility that are ubiquitously e, Xenopus/Amphibian,pressed in eukaryotic cells. There are 3 main actin...
Testicular receptor 2 (TR2) is a member of the orphan nuclear receptor family. TR2 is widely e, Xenopus/Amphibian,pressed at a low level throughout the adult...
Cyclin-dependent kinase 1 (CDK1) plays a key role in the control of the eukaryotic cell cycle. CDK-1 is required in higher cells for entry into S-phase and...
SYT1 (Synaptotagmin) is widely regarded as the primary calcium sensor for synaptic vesicle e, Xenopus/Amphibian,ocytosis. Synaptotagmin can be phosphorylated...
The 5'-nucleotidase cytosolic II (NT5C2) has a critical role in the maintenance of a constant composition of intracellular purine/pyrimidine nucleotides in...
Glutamate [NMDA] receptor subunit epsilon-2 (N-methyl D-aspartate receptor subtype 2B receptor or NMDA NR2B) is a NMDA receptor subtype of glutamate-gated...
Tumor necrosis factor alpha (TNF-alpha) is a cytokine that binds to the TNF-R1 and TNF-R2 receptors. TNF-alpha is mainly secreted by macrophages and induces...
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