The nociceptin receptor (KOR-3) is the receptor for the neuropeptide nocipeptin/orphanin FQ. KOR-3 has a potential role in modulating a number of brain...
Nociceptin is the ligand of the opioid receptor-like receptor (OPRL1). Nociceptin acts as a transmitter in the brain by modulating nociceptive and locomotor...
HSP-90 beta (Heat shock protein HSP 90-beta) is a homodimer with ATPase activity and functions as a molecular chaperone. HSP-90 beta is involved in the...
Aquaporin-2 (AQP-2) forms a water specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby...
Ubiquitin C-terminal hydrolase 1 (UCHL1) cleaves ubiquitin from other molecules. Genetic knockout of UCHL1 in mice results in a motor neuron degeneration...
Tyrosine hydro, Xenopus/Amphibian,ylase (TH) catalyzes the conversion of tyrosine to L-DOPA, which is the rate limiting step in the biosynthesis of...
INHA (Inhibin alpha) is a 366 amino acid long (~40kD) protein, regulates endocrin secretion. It is involved in regulating a number of diverse functions such...
RAB10 (Ras-related protein Rab-10) belongs to the RAS superfamily of small GTPases. RAB proteins localize to e, Xenopus/Amphibian,ocytic and endocytic...
Bcl-2 blocks cell death following a variety of stimuli and confers a death-sparing effect to certain hematopoietic cell lines following growth factor...
SMAD3 (Mothers against decapentaplegic homolog 3) is a tumor suppressor protein. SMAD proteins are signal transducers and transcriptional modulators that...
PRDM1/Blimp1 (PR domain zinc finger protein 1) is a repressor of beta-interferon gene e, Xenopus/Amphibian,pression. This action is e,...
ERK1 and ERK2 (E, Xenopus/Amphibian,tracellular signal-regulated kinase 1 and 2) are members of the MAP kinase signal transduction pathway. The activation of...
BDH1 (3-hydro, Xenopus/Amphibian,ybutyrate dehydrogenase, type 1) belongs to the short-chain dehydrogenase/reductase gene family. This protein forms a...
PP-1A (Serine/threonine-protein phosphatase PP1-alpha catalytic subunit) is a 330 amino acid protein (~38 kD). It is essential for cell division, and...
FAK (Focal adhesion kinase) is a 1074 -amino acid protein (~118 kDa). It is a member of the FAK subfamily of protein tyrosine kinases but lacks significant...
Rab25 is a 28 kDa protein, belongs to the small GTP-ase superfamily. Members of the Ras-related superfamily of GTP binding proteins which includes Ras, Rho,...
CHD3 (Chromodomain-helicase-DNA-binding protein 3) is a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin...
NFKB p65 (Nuclear factor NF-kappa-B p65 subunit) is a pleiotropic transcription factor. It is present in almost all cell types and is involved in many...
JAK3 (Janus kinase 3) is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal...
PTEN (Phosphatase and tensin homolog) is a dual-specificity protein phosphatase, dephosphorylating tyrosine-, threonine- and serine-phosphorylated proteins....