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Ah Receptor (Aryl Hydrocarbon Receptor, AHR)

Ah Receptor (Aryl Hydrocarbon Receptor, AHR)

Cat no: A1059-72X

Supplier: United States Biological
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The Ah Receptor belongs to a family of proteins comprised of its dimerization partner ARNT (HIF-1 Beta) and the Drosophila proteins PER and SIM. All of these proteins share an N-terminal sequence of ~200 amino acids termed the PAS domain. This receptor, found in a variety of tissues, binds to a specific DNA enhancer sequence and initiates transcription of the mRNA for the cytochrome P-450 (CYPIA1) gene. Positive Control: Mouse liver cytosol Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: A1059-72X
Reactivities: Mouse
Hosts: Rabbit
Applications: Western Blot
Size: 100ul
Form: Tris-citrate/phosphate buffer, pH 7-8
P type: Pab
Purity: Purified by immunoaffinity chromatography.
Alternative names: Dioxin Receptor
References: 1. Jain, S. et al. Potent transactivation domains of the Ah receptor and the Ah receptor nuclear translocator map to their carboxy termini. Journal of Biological Chemistry. 269 (50): 31518-24, 1994. 2. Schmidt, J.V., et al. Characterization of a murine Ahr null allele: Involvement of the Ah receptor in hepatic growth and development. Proc. Natl. Acad. Sci. USA. 93: 6731-6736,
Additional info: This antibody is specific for AHR. Species Crossreactivity: Recognizes mouse AHR. Other species have not been tested.

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