ALOX5AP (Arachidonate 5-lipoxygenase-activating Protein, FLAP, MK-886-binding Protein)

Cat no: A1359-76K

Supplier: United States Biological

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This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:128,000 Western Blot: 1:128,000 & 0.1-0.3ug/ml Immunohistochemistry (Formalin fixed paraffin embedded): 3.75ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Catalogue number:	A1359-76K
Reactivities:	Human
Hosts:	Goat
Applications:	ELISA, Immunohistochemistry, Western Blot
Size:	50ug
Form:	Supplied as a liquid in Tris saline buffer, pH 7.3, 0.5% BSA, 0.02% sodium azide.
P type:	Pab
Purity:	Purified by immunoaffinity chromatography.
Additional info:	Recognizes human ALOX5AP. Species sequence homology: Canine

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ALOX5AP (Arachidonate 5-lipoxygenase-activating Protein, FLAP, MK-886-binding Protein)

Cat no: A1359-76K

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