A non-selective ion channel blocker with broad fungicidal activity. Amiodarone induces an immediate influx of Ca2+ in Saccharomyces cerevisiae, followed by mitochondrial fragmentation and cell death. Also acts as an autophagy inducer.
Solubility:
H2O (50mg/ml)
Molecular Weight:
~681.77
Catalogue number:
A1381-62B
Size:
500mg
Form:
Supplied as a solid.
Purity:
~98% (TLC)
References:
1. Williams, A., et al. (2008). Nat. Chem. Biol. 4, 295-305. 2. Zhang, L., et al. (2007). Proc. Natl. Acad. Sci. USA 104, 19023-19028.