A selective, competitive HMG-CoA reductase inhibitor. The only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.
Solubility: DMSO, Methanol
Melting Point:
>220 degrees C (dec)
Method for Determining Identity:
Proton NMR (DMSO-d6) Spectroscopic and Mass Spectrometric Analysis
TLC Conditions:
SiO2: Dichloromethane: Methanol: Ammonium Hydroxide= 8: 2: 0.3; Visualized with UV and AMCS; Single spot; Rf=0.35.
Specific Rotation:
-8.2 (c=1, DMSO)
Elemental Analysis:
%C: 67.14%, %H: 5.98, %N: 4.57
Storage and Stability:
May be stored at RT for short-term only. Long-term storage is recommended at -20 degrees C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Toxicity and Hazards:
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