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CD3 (CDE3 CD3-epsilon T-cell surface glycoprotein CD3 epsilon chain T-cell surface antigen T3/Leu-4 epsilon chain CD3e)

Cat no: 168087

CD3 (CDE3 CD3-epsilon T-cell surface glycoprotein CD3 epsilon chain T-cell surface antigen T3/Leu-4 epsilon chain CD3e)

The CDE3 gene encodes the CD3-epsilon polypeptide (also known as CD3, T-cell surface glycoprotein CD3 epsilon chain,T-cell surface antigen T3/Leu-4 epsilon chain and CD3e), which together with CD3-g, -d and -z, and the T-cell receptor a/b and g/d heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling recognition to several intracellular signal-transduction pathways. The genes encoding the e, g and d polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. CD3 is ideal for Immunology and Stem Cell research.\n\nApplications:\nSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.\n\nRecommended Dilution:\nELISA: 1:20,000\nWestern Blot: 1:500-1:2000\nImmunohistochemistry: 1:50\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

168087

Size

100ul

Applications

ELISA, IHC, WB

Hosts

Rabbit

Reactivities

Hum, Can, Fel, NHP

Form

Supplied as a liquid, 0.1% sodium azide.

P Type

Mab

Purity

Supernatant

Isotype

IgG

Additional Info

Recognizes human CD3. Species Crossreactivity: monkey, equine, canine and feline.

Alternative Names

CDE3 CD3-epsilon T-cell surface glycoprotein CD3 epsilon chain T-cell surface antigen T3/Leu-4 epsilon chain CD3e

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