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CD54 (ICAM-1, Intercellular Adhesion Molecule 1, Human Rhinovirus Receptor, Precursor, BB2, Major Group Rhinovirus Receptor, P3.58)

Cat no: C2409-46

CD54 (ICAM-1, Intercellular Adhesion Molecule 1, Human Rhinovirus Receptor, Precursor, BB2, Major Group Rhinovirus Receptor, P3.58)

ICAM-1 permits antigen- independent adhesion between lymphocytes and their targets. The LFA-1 binding site is located in domain 1 of ICAM-1. The CD54 antigen is a membrane glycoprotein with a wide tissue distribution that includes vascular endothelium and many cells of the immune system. CD54 is weakly expressed on resting peripheral blood lymphocytes. Upon activation by mitogens, the CD54 antigen is strongly expressed on B-cells, T-cells, macrophages and granulocytes. CD54 is the receptor for rhinoviruses and malaria.\n\nApplications: \nSuitable for use in Flow Cytometry. May be used to study cell-cell interactions. Other applications have not been tested.\n\nRecommended Dilutions:\nFlow Cytometry: 1ug to stain 1x10e6 cells\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

C2409-46

Size

200ug

Applications

FC

Hosts

Mouse

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.2, 1% BSA, 0.09% sodium azide.

P Type

Mab

Purity

Purified by Protein G affinity chromatography

Isotype

IgG1

References

1. Hogg, N. et al., Cell 68:71 (1992). 2. Hogg, N. et al., J. Cell Biology 116:1527 (1992)

Additional Info

Recognizes the human intercellular adhesion molecule ICAM-1 (85

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