Supplier:
United States BiologicalCat no: D0101-01A
D4-GDI (D4 GDP-Dissociation Inhibitor)
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Exclusive Biosave savings/discounts
SPECIFICATIONS
Catalog Number
D0101-01A
Size
100ug
Applications
FC, IHC, IP, WB
Hosts
Mouse
Reactivities
Hum, Mouse
Form
Supplied as a liquid in PBS containing 0.02% sodium azide.\n
P Type
Mab
Purity
Purified by Protein G affinity chromatography.
Isotype
IgG2b
References
Product Specific Literature References\n1. The protein kinase PKB/Akt regulates cell survival and apoptosis by inhibiting Bax conformational change: H. Yamaguchi & H.G. Wang; Oncogene 20, 7779 (2001) \n2. Interference with PDK1-Akt survival signaling pathway by UCN-01 (7-hydroxystaurosporine): S. Sato, et al.; Oncogene 21, 1727 (2002) \n3. RhoGDI2 is an invasion and metastasis suppressor gene in human cancer: J.J. Gildea, et al.; Cancer Res. 62, 6418 (2002) \n4. Molecular cloning and characterization of Bif-1. A novel Src homology 3 domain-containing protein that associates with Bax: S.M. Cuddeback, et al.; J. Biol. Chem. 276, 20559 (2001) \n\nGENERAL LITERATURE REFERENCES\n1. Cleavage and nuclear translocation of the caspase 3 substrate Rho GDP-dissociation inhibitor, D4-GDI, during apoptosis: R.J. Krieser & A. Eastman; Cell Death Differ. 6, 412 (1999) \n2. Rho guanine dissociation inhibitors: pivotal molecules in cellular signalling: B. Olofsson; Cell. Signal. 11, 545 (1999)\n3. GDP dissociation inhibitor D4-GDI (Rho-GDI 2), but not the homologous rho-GDI 1, is cleaved by caspase-3 during drug-induced apoptosis: F. Essmann, et al.; Biochem. J. 346 Pt 3, 777 (2000)
Additional Info
Recognizes human and mouse D4-GDI. Detects a band of ~23kDa by Western blot.\n
SUPPLIER INFO
Applications
ELISA, ICC, WB
Hosts
Rabbit
Reactivities
Hum
Applications
FC, IP, WB
Hosts
Rabbit
Reactivities
Hum
Applications
IHC
Hosts
Rabbit
Reactivities
Hum
Applications
FC, ICC, IHC, WB
Hosts
Mouse
Reactivities
Hum, Mouse, Rat
Applications
ICC, WB
Hosts
Rabbit
Reactivities
Hum
Applications
FC, IP, WB
Hosts
Rabbit
Reactivities
Mouse, Rat
Applications
ELISA, WB
Hosts
Goat
Reactivities
Hum
Applications
ELISA, IHC, WB
Hosts
Mouse
Reactivities
Hum
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